Homogenizer
Micotec
Co., Ltd. has been producing various homogenizers for more than 40 years.
And now, we are the only company that produces and sells homogenizers as
a main business in Japan.
Our homogenizers "Physcotron" have the strong advantage of "micro-processing technology of the blade edge". In contrast, other homogenizer manufacturers mainly depend on enhancing the power supply which makes louder noises or even breaks your sample.
Cell Crushing and Extraction
Universal homogenizer Physcotron can break up to a few microns of cells and the nucleus therein. However, problems such as DNA shredding will occur if the crushing power is too strong. So it is very important to adjust the blade edge according to the object. In our customizing service, we process the rotational inner blade (part of the generator) to suit user's purpose.
This caring support enables you to obtain the extraction rate of the desired object at a high level that can not be reached by ready-made products.
- Extraction of DNA, RNA, protein, and etc.
- Extraction for component analysis
- Meat crushing
- Grain crushing
- Rice leaf crushing
- Crushing of processed food
- Crushing of sugar-coated tablets
- Tissue crushing
For extraction of DNA and RNA, Frozen Cell Crusher "Cryo-Press" is most suitable. Please see this page.
Dispersion
Physcotron is also good at dispersing the sample (dispersion system) while crushing it in liquid (solvent system). It often happens that particles can stick together and agglomerate without maintaining the state of small particles.
This happens when the zeta potential of the particles is low. But our know-how on zeta potential has improved the ability of homogenizer from this angle. Please leave the crushing the sample with such particle characteristics to us.
Refinement and homogenization
There are various methods for homogenization, and inexpensive equipments can be good enough to just homogenize sample. However, refinement is very difficult, and there are many cases that refinement cannot be done at all because you select a wrong equipment.
Physcotron is basically an equipment for refinement. In order to refine, the sample moving around should be kept in the generator and crushed. In contrast, for homogenization, sample should move faster to make more opportunity to be mixed. However, It is obviously necessary to homogenize while refining. Therefore, how efficiently both homogenization and refinement can be performed simultaneously determines the ability of the homogenizer. In this respect, the design of the Physcotron generator part boasts the highest and unrivaled level.
Product Lineup
In the table below, four drive units on the left are compatible with any of generator shafts on the right.
| Drive units | Generator shafts | ||
|---|---|---|---|
 NS-52 Standard type |
 NS-52K Standard type with a rotational indicator |
Open type | |
| Small volume | NS-10, NS-10M, NS-10G | ||
| Universal | NS-20, NS-20M, NS-20G | ||
| Sharp | NS-20S | ||
| Ultrasonic wave | NS-30U, NS-30UG | ||
| Shaft for separate-type generators | 10P, 20P | ||
| Closed type | |||
 NS-57 Silent type |
 NS-57S Silent type with a timer & rotational indicator |
Small volume | NS-10G, NS-10GM |
| Universal | NS-20G, NS-20GM | ||
| Sharp | NS-20SG, NS-20SGM | ||
| Agitation | NS-20MG | ||
| Ultrasonic | NS-30UG | ||
| Multiplexed ultrasonic | NS-35UG | ||
| Large volume | NS-35G | ||
| Shaft for separate-type generators | 10TP, 20TP | ||
In the table below, two drive units on the left are compatible with any of generator shafts on the right.
| Drive units | Micro-shafts | |
|---|---|---|
 NS-310E3 Handy Micro-homogenizer Standard type |
0.05 - 2 ml | NS-3 |
| 0.1 - 5 ml | NS-4 | |
| 0.5 - 50 ml | NS-7 | |
Please let us know your application. We are happy to suggest the best combination of drive-unit and generator!
Application
- Basic medicine: Skins, heart muscles, splanchnic tissues, and cells (the extraction of DNA and RNA).
- Agriculture, forestry and fisheries: Grain cereals, seeds, fruits, leaves, stalks, roots, and animal tissues.
- Food: Processing development (meat, fish, and etc.) for analysis, inspection, and quality control.
- Electrical and Electronics: Dispersion of magnetic materials. Production and research of new materials.
- Chemical products: Production and research of emulsifiers and pigments.
- Environment: Homogenization and dispersion of sewage.
- Microbial system: Crushing and dispersion of cultured microorganisms.
- Drugs and medicines: Crushing of tablets. Purification of vaccines and yeasts.
